Body weight gain rate in patients with Parkinson's disease and deep brain stimulation
Identifieur interne : 000513 ( Main/Corpus ); précédent : 000512; suivant : 000514Body weight gain rate in patients with Parkinson's disease and deep brain stimulation
Auteurs : Michela Barichella ; Agnieszka M. Marczewska ; Claudio Mariani ; Andrea Landi ; Antonella Vairo ; Gianni PezzoliSource :
- Movement Disorders [ 0885-3185 ] ; 2003-11.
English descriptors
Abstract
We evaluated body weight changes in patients with Parkinson's disease (PD) after electrode implantation for deep brain stimulation (DBS) in the subthalamic nucleus (STN) in relation to clinical improvement. Thirty PD patients who received STN DBS were included (22 men, 8 women; mean age, 60.0 ± 7.1 years; mean PD duration, 13.5 ± 3.7 years; mean body mass index [BMI], 21.6 ± 3.0 kg/m2). Body weight, physical activity, and Unified Parkinson's Disease Rating Scale (UPDRS) scores were noted before and 3 and 12 months after the procedure. Significant weight gain occurred in 29 patients; the mean increase was 14.8 ± 9.8% of initial body weight in 1 year. Of the patients, 46.5% reported weight gain in the first 3 months, 21.4% gradual weight gain in the first 6 months, and 32.1% a slow increase for 1 year. Mean BMI increased up to 24.7 ± 3.7 kg/m2. After 1 year, mean UPDRS motor score improved significantly in off and in on; and therapy complications improved by 91.0 ± 17.0%. BMI changes at 3 and 12 months were significantly correlated to dyskinesia score changes, and levodopa dosage was not. In PD, STN DBS produces not only symptom control, but also weight gain. DBS candidates should be given nutritional counseling before the intervention to prevent rapid and/or excessive weight gain. © 2003 Movement Disorder Society
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DOI: 10.1002/mds.10543
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ISTEX:96A7379AAB5A072E651747A4255A170F4708C6F4Le document en format XML
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Thirty PD patients who received STN DBS were included (22 men, 8 women; mean age, 60.0 ± 7.1 years; mean PD duration, 13.5 ± 3.7 years; mean body mass index [BMI], 21.6 ± 3.0 kg/m2). Body weight, physical activity, and Unified Parkinson's Disease Rating Scale (UPDRS) scores were noted before and 3 and 12 months after the procedure. Significant weight gain occurred in 29 patients; the mean increase was 14.8 ± 9.8% of initial body weight in 1 year. Of the patients, 46.5% reported weight gain in the first 3 months, 21.4% gradual weight gain in the first 6 months, and 32.1% a slow increase for 1 year. Mean BMI increased up to 24.7 ± 3.7 kg/m2. After 1 year, mean UPDRS motor score improved significantly in off and in on; and therapy complications improved by 91.0 ± 17.0%. BMI changes at 3 and 12 months were significantly correlated to dyskinesia score changes, and levodopa dosage was not. In PD, STN DBS produces not only symptom control, but also weight gain. DBS candidates should be given nutritional counseling before the intervention to prevent rapid and/or excessive weight gain. © 2003 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Michela Barichella MD</name><affiliations><json:string>Centro per la Malattia di Parkinson ed i Disturbi del Movimento, Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy</json:string></affiliations></json:item><json:item><name>Agnieszka M. 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Thirty PD patients who received STN DBS were included (22 men, 8 women; mean age, 60.0 ± 7.1 years; mean PD duration, 13.5 ± 3.7 years; mean body mass index [BMI], 21.6 ± 3.0 kg/m<sup>2</sup>). Body weight, physical activity, and Unified Parkinson's Disease Rating Scale (UPDRS) scores were noted before and 3 and 12 months after the procedure. Significant weight gain occurred in 29 patients; the mean increase was 14.8 ± 9.8% of initial body weight in 1 year. Of the patients, 46.5% reported weight gain in the first 3 months, 21.4% gradual weight gain in the first 6 months, and 32.1% a slow increase for 1 year. Mean BMI increased up to 24.7 ± 3.7 kg/m<sup>2</sup>. After 1 year, mean UPDRS motor score improved significantly in <i>off</i> and in <i>on</i>; and therapy complications improved by 91.0 ± 17.0%. BMI changes at 3 and 12 months were significantly correlated to dyskinesia score changes, and levodopa dosage was not. In PD, STN DBS produces not only symptom control, but also weight gain. DBS candidates should be given nutritional counseling before the intervention to prevent rapid and/or excessive weight gain. © 2003 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Body weight gain rate in patients with Parkinson's disease and deep brain stimulation</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Deep Brain Stimulation and Weight Gain Rate</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Body weight gain rate in patients with Parkinson's disease and deep brain stimulation</title></titleInfo><name type="personal"><namePart type="given">Michela</namePart><namePart type="family">Barichella</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Centro per la Malattia di Parkinson ed i Disturbi del Movimento, Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Agnieszka M.</namePart><namePart type="family">Marczewska</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Centro per la Malattia di Parkinson ed i Disturbi del Movimento, Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Claudio</namePart><namePart type="family">Mariani</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Centro per la Malattia di Parkinson ed i Disturbi del Movimento, Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Andrea</namePart><namePart type="family">Landi</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Neurosurgery Department, Monza Hospital, Monza, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Antonella</namePart><namePart type="family">Vairo</namePart><namePart type="termsOfAddress">BSc</namePart><affiliation>Centro per la Malattia di Parkinson ed i Disturbi del Movimento, Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gianni</namePart><namePart type="family">Pezzoli</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Centro per la Malattia di Parkinson ed i Disturbi del Movimento, Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy</affiliation><description>Correspondence: Director of Department of Neuroscience, Parkinson Institute, Istituti Clinici di Perfezionamento, Via Bignami, 1, 20126 Milano, Italy</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2003-11</dateIssued><dateCaptured encoding="w3cdtf">2002-12-20</dateCaptured><dateValid encoding="w3cdtf">2003-05-19</dateValid><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">1</extent><extent unit="references">11</extent><extent unit="words">2399</extent></physicalDescription><abstract lang="en">We evaluated body weight changes in patients with Parkinson's disease (PD) after electrode implantation for deep brain stimulation (DBS) in the subthalamic nucleus (STN) in relation to clinical improvement. Thirty PD patients who received STN DBS were included (22 men, 8 women; mean age, 60.0 ± 7.1 years; mean PD duration, 13.5 ± 3.7 years; mean body mass index [BMI], 21.6 ± 3.0 kg/m2). Body weight, physical activity, and Unified Parkinson's Disease Rating Scale (UPDRS) scores were noted before and 3 and 12 months after the procedure. Significant weight gain occurred in 29 patients; the mean increase was 14.8 ± 9.8% of initial body weight in 1 year. Of the patients, 46.5% reported weight gain in the first 3 months, 21.4% gradual weight gain in the first 6 months, and 32.1% a slow increase for 1 year. Mean BMI increased up to 24.7 ± 3.7 kg/m2. After 1 year, mean UPDRS motor score improved significantly in off and in on; and therapy complications improved by 91.0 ± 17.0%. BMI changes at 3 and 12 months were significantly correlated to dyskinesia score changes, and levodopa dosage was not. In PD, STN DBS produces not only symptom control, but also weight gain. DBS candidates should be given nutritional counseling before the intervention to prevent rapid and/or excessive weight gain. © 2003 Movement Disorder Society</abstract><note type="funding">Fondazione Grigioni peril Morbo di Parkinson</note><subject lang="en"><genre>Keywords</genre><topic>deep brain stimulation</topic><topic>Parkinson's disease</topic><topic>weight gain</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>11</number></detail><extent unit="pages"><start>1337</start><end>1340</end><total>4</total></extent></part></relatedItem><identifier type="istex">96A7379AAB5A072E651747A4255A170F4708C6F4</identifier><identifier type="DOI">10.1002/mds.10543</identifier><identifier type="ArticleID">MDS10543</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2003 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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